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AP Business News Digest

MICHELLE CHAPMAN
September 22, 2025

Here are the AP's top business stories that have moved or are planned to move today. All times U.S. Eastern. For up-to-the minute information on AP's coverage, visit AP Newsroom's Coverage Plan.

Financial Markets

Wall Street drifts around its records as its relentless rally takes a breath

SUMMARY: U.S. stocks are drifting as Wall Street's big rally lets off the accelerator. The S&P 500 dipped 0.2% Monday. The Dow Jones Industrial Average fell 103 points, and the Nasdaq composite was virtually unchnaged. It's only a modest pullback when compared with the surge that stocks have enjoyed hitting a bottom in April, and all three indexes are still near their records set on Friday. Some of the markets' strongest action was among companies announcing purchases of each other. Pfizer said it would buy Metsera and its pipeline of potential obesity treatments, while Compass agreed to merge with Anywhere Real Estate.

WORDS: 553 - MOVED: 09/21/2025 11:52 p.m. EDT

https://newsroom.ap.org/detail/WallStreetdriftsarounditsrecordsasitsrelentlessrallytakesabreath/1b2f59b28860658af42d0ce003226cf7/text

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US--Philanthropy-United Nations

Big foundations and nonprofits still flood to the sidelines of a diminished United Nations

SUMMARY: The United Nations will draw foundations and nonprofits to New York for a packed schedule of events on the sidelines of its General Assembly starting Sept. 22. But uncertainty over its future and foreign aid commitments have already had an impact. The Gates Foundation has delayed an annual report about progress toward global development goals. The Clinton Global Initiative is changing its format to focus on new programs. Despite these challenges, Kevin Sheekey, a senior adviser to billionaire Mike Bloomberg., says the U.N. General Assembly is still the only place that the whole world gets together and that is valuable.

WORDS: 850 - MOVED: 09/20/2025 8:05 a.m. EDT

https://newsroom.ap.org/detail/BigfoundationsandnonprofitsstillfloodtothesidelinesofadiminishedUnitedNations/5d34a749f4b189238f5caf11caf8152a/text

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US-Trump-TikTok

Trump reveals Murdochs and Dell could potentially take part in TikTok deal

SUMMARY: President Donald Trump has mentioned that billionaires like Rupert Murdoch and Michael Dell could be part of deal in which the U.S. will take control of TikTok. Trump discussed the deal on Fox News, highlighting the potential involvement of Murdoch and his son Lachlan. He also mentioned Oracle founder Larry Ellison's involvement, which was previously disclosed. The deal aims to keep TikTok operating in the U.S. amid concerns about data security and manipulation by Chinese authorities. Congress has passed legislation for a TikTok ban, but Trump has signed orders allowing it to operate while negotiations continue. Trump credits TikTok for helping him connect with young voters.

WORDS: 463 - MOVED: 09/21/2025 1:58 p.m. EDT

https://newsroom.ap.org/detail/TrumprevealsMurdochsandDellcouldpotentiallytakepartinTikTokdeal/c175ddc4bdeaa269543870f1227cd0d9/text

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Pfizer-Metsera Acquisition

Pfizer amps up push into obesity treatments with $4.9B deal for Metsera

SUMMARY: Five months after ending development of its own obesity treatment, Pfizer is accelerating its push into the rapidly growing field with a nearly $5-billion acquisition. The COVID-19 vaccine maker said Monday that it will pay $47.50 in cash for each share of development-stage drugmaker Metsera. That represents a premium of more than 42% to Metsera's closing price Friday. Pfizer also could pay an additional $22.50 per share depending on how Metsera's product pipeline develops. Metsera has no products on the market, but its pipeline includes four programs in clinical development. Obesity treatment demand has soared in recent years.

WORDS: 331 - MOVED: 09/22/2025 7:44 a.m. EDT

https://newsroom.ap.org/detail/PfizerampsuppushintoobesitytreatmentswithBdealforMetsera/e85141f89b670b8d9a7520de3a2fd7c5/text

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US--Oracle-Leadership

Oracle names Magouyrk and Sicilia as CEOs; Catz to become executive vice chair of the board

SUMMARY: Oracle has named Clay Magouyrk and Mike Sicilia as CEOs, with current CEO Safra Catz becoming executive vice chair of the technology company's board.Oracle said Monday that Magouyrk previously served as president of Oracle Cloud Infrastructure. Sicilia was president of Oracle Industries and joined the company when Oracle acquired Primavera Systems.

WORDS: 269 - MOVED: 09/22/2025 8:56 a.m. EDT

https://newsroom.ap.org/detail/OraclenamesMagouyrkandSiciliaasCEOsCatztobecomeexecutivevicechairoftheboard/69ad588693f0c8de9fe6dcf4632037d3/text

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AS--Japan-Nissan

Japanese automaker Nissan is developing vehicles with self-driving technology

SUMMARY: Japanese automaker Nissan is developing vehicles with self-driving technology as it works to turn around its struggling auto business. The technology is set to be available to drivers in 2027. Previous Nissan self-driving technology was designed for freeway driving, where the lanes are clearly marked and easier to decipher. The new technology is designed for congested, unpredictable city streets. It's an already-crowded field. The self-driving car market is estimated to reach $2 trillion by 2030, according to market researcher IndustryARC.

WORDS: 280 - MOVED: 09/21/2025 11:36 p.m. EDT

https://newsroom.ap.org/detail/JapaneseautomakerNissanisdevelopingvehicleswithselfdrivingtechnology/aeaff0f42bd69a900d770a3433677053/text

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<END>

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