Rare Disease Biotech Offers Access Ahead of Key Milestone

This late-stage biotech is gearing up for Phase 2 trials with an FDA-designated orphan drug. It's already drawing comparisons to recent billion-dollar exits. Backed by a proven biotech incubator, it's now offering early access to its raise.

What You Need to Know About Annuities

Christine Benz & Margaret Giles of Morningstar
October 01, 2025

Retirement researchers are often enthusiastic about annuities, but many consumers are reasonably skeptical. Here to discuss basic information about annuities and their pros and cons is Christine Benz, Morningstar's director of personal finance and retirement planning.

This interview has been edited for length and clarity.

Q: How do income annuities work, and how they are different from investing in something that pays out income like bonds?

A: An annuity is a contract with an insurance company. In the most basic annuity type, income annuities, you give the insurance company a pool of your money, and they send it back to you as a stream of income over your lifetime. Those types of products give you more income than you could earn by investing in a bond.

They do that because you benefit in the annuity by what's called "longevity risk pooling," which means that some people who are buying that same annuity will die sooner, which enlarges the payout for the whole group of you. If you're the one who lives to be 99, you're the winner in that situation. That's one reason that payouts are higher than you'd see for traditional fixed-income instruments. The other big reason is that if you buy an annuity, your money is gone, effectively. You get cash flows, but you can't get your principal back. In contrast, when you buy a bond, you receive income, but you receive your principal back at the end.

Q: How can these types of annuities help with retirement planning?

A: These very basic income annuities can be helpful in terms of addressing a household's basic living expenses. Say my household basic expenses--housing, taxes, healthcare--total $40,000, and Social Security is going to give me another $30,000 of that $40,000. I could buy an annuity that will supply me with $10,000 a year to help meet those basic cash flow needs. That's an elegant use of an annuity, and it can help retirees figure out how much they would want to put into such a product, by examining how much they actually need from it.

Q: Savings annuities, or "deferred annuities," allow investors to get market exposure in addition to income. What are some key savings annuity types?

A: The most familiar one is a variable annuity where you're in control of the investment allocations. There are also increasingly popular "fixed index" annuities, where you get market exposure, but there are caps on your gains. There are also caps on your losses. Registered index-linked annuities fall between those two product types on the risk spectrum.

Q: These products are more complicated than income annuities, and they carry more risk and higher costs. How can investors make sure they know what they're getting into with these products?

A: Typically, these products carry really long contracts with lots of fine print. That can be very difficult for consumers to wade through. You can hire an objective third party to help you understand what you might be getting into.

At a minimum, write down all of your questions. There are no stupid questions in this context, because transparency isn't there for consumers. Ask about costs, withdrawals, and what you're getting with this product that you couldn't get with a very vanilla investment portfolio that would also give you more liquidity and more access to your funds. Until you have exhausted all of those questions, don't sign on the bottom line. You also want to ask about the financial strength of the insurance company backing the annuity, because this is a long-term relationship. You need to make sure that they're able to make good on whatever promises they're making.

Q: What are the tax implications of annuities?

A: It depends on the account that you use to fund the annuity, but generally, you will owe taxes. You get some tax deferral as long as the funds are in the annuity, and then you'll owe taxes on any money that hasn't been taxed yet. If you put pretax dollars into an annuity and it makes investment gains, all of your withdrawals will be taxable at your ordinary income tax rate.

_____

This article was provided to The Associated Press by Morningstar. For more personal finance content, go to https://www.morningstar.com/personal-finance

Christine Benz is Morningstar's director of personal finance and retirement planning.

Related links:

Continue Reading...

Popular

FBI Director Kash Patel Bought 2 Stocks In 2025 — One's Already A Meme Favorite

FBI Director Kash Patel was asked about two stocks he bought earlier this year by a member of Congress on Wednesday and gave a surprising answer. The transactions come as members of Congress are working on legislation to ban lawmakers and cabinet members from buying and selling stocks.

Nvidia to invest $5 billion in Intel; companies will work together on AI infrastructure and PCs

NEW YORK (AP) — Nvidia, the world's leading chipmaker, announced on Thursday that it's investing $5 billion in Intel and it will collaborate with the struggling semiconductor company on products.

Biotech With Multiple Orphan Drugs Is Quietly Opening Its Doors - Ad

A promising biotech developing treatments for rare childhood brain diseases is opening a new raise. Its lead drug has fast-track status, orphan designations, is nearing Phase 2 and backed by a Global Integrator.

Here's How Much You Would Have Made Owning Applied Industrial Techs Stock In The Last 5 Years

Applied Industrial Techs (NYSE: AIT) has outperformed the market over the past 5 years by 21.84% on an annualized basis producing an average annual return of 36.48%. Currently, Applied Industrial Techs has a market capitalization of $9.78 billion.

Hims & Hers Scrutinized For Marketing Its Product As Similar To Ozempic, Wegovy

FDA warns Hims & Hers that its semaglutide products are misbranded due to misleading claims and asks for corrective steps within 15 days.

The Tesla Shock Nobody Sees Coming - Ad

While headlines scream "Tesla is doomed"...Jeff Brown has uncovered a revolutionary AI breakthrough buried inside Tesla's labs. One that is helping AI escape from our computer screens and manifest itself here in the real world all while creating a 25,000% growth market explosion starting as early as October 23rd.

Shiba Inu Lead Kaal Dhairya Calls $4 Million Hack 'Serious Incident' — Vitalik Buterin Says Focus On Low-Risk DeFi Than Memecoins

Kaal Dhairya, the lead developer of the Shiba Inu (CRYPTO: SHIB) ecosystem, labeled the recent hack incident as “serious” on Sunday, but indicated that the team was able to contain the immediate damage.

Why Rivian Automotive Stock Is Gaining Today?

Rivian stock climbs after breaking ground on a multibillion-dollar Georgia EV plant.

Nvidia Is About to Shock the World: October 23rd - Ad

Jeff Brown, the tech legend who picked shares of Nvidia in 2016 before they jumped by more than 22,000%, is warning everyone to... Mark this date on your calendar: October 23rd! That's when Nvidia could help send shares of this Elon Musk supplier skyrocketing higher.

Microsoft resolves European Union probe into Teams

LONDON (AP) — European Union regulators have accepted Microsoft's to Teams, resolving a long-running antitrust investigation that targeted the company's messaging and videoconferencing app.

3 Gold Mining Stocks Shine As Prices Hit Records

Gold mining stocks Anglogold Ashanti, Coeur Mining, and New Gold join the top 10% for quality as gold prices hit fresh highs.

Gold Is Being Reintroduced Into the Monetary System - Ad

While the media focuses on political scandals, inflation and coming up with ridiculous acronyms "TACO"... Smart money is tracking a far bigger shift: a gold revaluation is quietly underway. Garrett Goggin, CFA, says this could trigger 100X moves in select miners - and he's identified four with the biggest upside.

Ex-Trump Lawyer Raises Alarms: 'I Have Never Been As Concerned As To Whether Our System Can Withstand The Pressure'

Abbe Lowell, a lawyer who once represented President Donald Trump's family, has expressed grave concerns over the potential harm the current administration could cause to the country's institutions.

US Attorney Erik Siebert Resigns After Refusing Trump Pressure To Pursue Criminal Case Against NY AG Letitia James: Report

U.S. Attorney Erik Siebert resigned after refusing Trump administration pressure to charge New York AG Letitia James without evidence, a move critics call political retribution.

The "Mar-A-Lago Accord" Is Now Underway - Ad

The global order is in chaos. And according to 40-year market veteran Dr. David Eifrig, the biggest controlled demolition of the old monetary order in history could now be here, too. That means if you don't take action today, your wealth could decline by 40%... (Yes, even your cash savings.)

Meta Unveils $499 Oakley Vanguard And $799 Ray-Ban Display Smart Glasses At Connect 2025: Gene Munster Says 'Best Bang For The Buck'

Meta unveiled its $499 Oakley Vanguard and $799 Ray-Ban Display smart glasses at Connect 2025, with Gene Munster calling the Ray-Ban model the "best bang for the buck" as competition with Apple heats up.

Is The LYFT Finally Heading To The Penthouse? Bullish Momentum Ahead?

Adhishthana.com analysis shows LYFT entering Phase 9 with a bullish breakout, setting the stage for a strong rally through 2026.

Elon's $25 Trillion Confession - Ad

Elon Musk: "Tesla will become a $25 trillion company." That would make Tesla 8x bigger than Apple today. How is that possible? He admits it's all thanks to this one AI breakthrough that will take AI out of our computer screens and manifest a 250x boom here in the real world.

Gov. Stein requests $13.5B more from Congress for Hurricane Helene recovery

FLAT ROCK, N.C. (AP) — North Carolina Gov. Josh Stein on Monday requested $13.5 billion more from Congress in recovery aid for almost a year after the historic storm, saying additional help is needed from Washington to address record amounts of damage and to get funds to the region quicker.

New England's shrimp industry is struggling, with fishermen catching few in 2025

PORTLAND, Maine (AP) — There's an effort underway to bring New England shrimp back to seafood customers — but fishermen have found few of the crustaceans, and the fishing industry that harvests them may face an even longer shutdown.

Why This Crypto Skeptic Had a Change of Heart - Ad

He used to make fun of crypto. Now... he says one $3 crypto could rise to $92 by next year.

China's Tech Stocks Surge As AI Spending Accelerates

Chinese tech stocks rallied as bets on AI lift sentiment. Alibaba, Baidu, JD, PDD, NIO, Li Auto, and XPeng stocks all rose, showing renewed confidence in China's tech and EV sectors.

Asian shares trade mixed after Wall Street sets new records

TOKYO (AP) — Asian shares traded mixed on Tuesday after Wall Street set new records as investor anticipation grew that the U.S. Federal Reserve will announce the first cut of the year on its main interest rate.

New Biotech Offering Targets $426B Rare Disease Market - Ad

The rare disease drug space is growing fast-and so is investor interest. With exclusivity, pricing power and major M&A moves, the rare disease space is getting interesting. This company has the science and the experience.

Will mortgage rates drop further after the Fed's rate cut? Not necessarily

LOS ANGELES (AP) — Hoping that mortgage rates will keep dropping following since last year? Don't bank on it.

Ethereum Faces Alt-Season Pressure: Why Fusaka Upgrade Could Be A Gamechanger

Ethereum is once again under the spotlight as traders declare the arrival of a fresh alt-season. With capital rotating into high-beta tokens like Solana, Avalanche, and meme coins, Ethereum (Crypto: ETH) finds itself squeezed between being the "blue-chip" altcoin and the slowest horse in a fast-moving race.

[Revealed] Trump's Next AI Executive Orders? - Ad

A White House insider with direct ties to Trump's inner circle just revealed what he calls "Manhattan II" - a potential $2.2 trillion AI initiative set to launch as soon as Oct 15. He says this could mirror past U.S. projects that minted fortunes - with small firms soaring 5,000% to 10,000% over two decades. And now he's giving away his #1 stock pick for free before the deadline.

Will electric tractors gain traction? At a pilot event for farmers, researchers see possibilities

EAST LANSING, Mich. (AP) — In the soft dirt of an indoor horseback riding ring last month, a group of farmers got ready to test drive a new piece of equipment: an electric tractor.

Rare Disease Biotech Offers Access Ahead of Key Milestone - Ad

This late-stage biotech is gearing up for Phase 2 trials with an FDA-designated orphan drug. It's already drawing comparisons to recent billion-dollar exits. Backed by a proven biotech incubator, it's now offering early access to its raise.

British department store Harrods warns customers that some personal details taken in data breach

LONDON (AP) — Harrods, the luxury British department store, has warned some customers that their personal data may have been taken in a breach of its online systems.

3 members of federal control board in Puerto Rico sue Trump and others for illegal firings

SAN JUAN, Puerto Rico (AP) — Three members of a federal control board overseeing Puerto Rico’s finances, by the administration of U.S. President Donald Trump, filed a lawsuit in federal court on Thursday alleging their firings were illegal.

Biotech With Multiple Orphan Drugs Is Quietly Opening Its Doors - Ad

A promising biotech developing treatments for rare childhood brain diseases is opening a new raise. Its lead drug has fast-track status, orphan designations, is nearing Phase 2 and backed by a Global Integrator.

Iraq's first industrial-scale solar plant opens in Karbala desert to tackle electricity crisis

KARBALA, Iraq (AP) — Iraq is set to open the country’s first industrial-scale solar plant Sunday in a vast expanse of desert in Karbala province, southwest of Baghdad.

Elizabeth Warren Says Measles Can Hit Record Highs, Slams RFK Jr.'s CDC Panel For Delaying Vaccine: 'How Does That Keep Our Kids Safe?'

Sen. Elizabeth Warren (D-Mass.) on Thursday criticized the Centers for Disease Control and Prevention's vaccine advisory panel following its controversial vote to delay the combined measles, mumps, rubella, and varicella or MMRV vaccine for children under 4 years old.

The Tesla Shock Nobody Sees Coming - Ad

While headlines scream "Tesla is doomed"...Jeff Brown has uncovered a revolutionary AI breakthrough buried inside Tesla's labs. One that is helping AI escape from our computer screens and manifest itself here in the real world all while creating a 25,000% growth market explosion starting as early as October 23rd.

Billionaire says $2.3 billion Banamex stake signals confidence in Mexico's economy

MEXICO CITY (AP) — A day after Citigroup announced it would sell a 25% stake in Banamex to billionaire Fernando Chico Pardo, the Mexican businessman said his $2.3 billion investment should be read as a sign of confidence in Mexico’s government and economic potential.

Google's top AI scientist says ‘learning how to learn’ will be next generation's most needed skill

ATHENS, Greece (AP) — A top Google scientist and 2024 Nobel laureate said Friday that the most important skill for the next generation will be “learning how to learn” to keep pace with change as transforms education and the workplace.

Nvidia Is About to Shock the World: October 23rd - Ad

Jeff Brown, the tech legend who picked shares of Nvidia in 2016 before they jumped by more than 22,000%, is warning everyone to... Mark this date on your calendar: October 23rd! That's when Nvidia could help send shares of this Elon Musk supplier skyrocketing higher.

'Bitcoin Bottom Day' Tomorrow Could Define Trend – Expert Predicts 70% Chance BTC Secures $100K Floor"

Bitcoin (CRYPTO: BTC) is trading near $115,000 as traders eye September 21, a date that could prove pivotal in shaping the crypto king's trajectory through the rest of 2025.

Trending Now

Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.

Copyright activatrade.ca
Privacy Policy | Terms of Service