Rare Disease Biotech Offers Access Ahead of Key Milestone

This late-stage biotech is gearing up for Phase 2 trials with an FDA-designated orphan drug. It's already drawing comparisons to recent billion-dollar exits. Backed by a proven biotech incubator, it's now offering early access to its raise.

3 BlackRock Debt Funds Dwindle In Quality Amid Falling Treasury Yields

Rishabh Mishra
September 16, 2025

Three BlackRock fixed-income closed-end funds experienced notable declines in their quality rankings this week, pushing each into the market's bottom decile for operational efficiency and financial health. This shift comes as U.S. Treasury yields have been declining, causing changes across the credit markets.

What Does Quality Ranking Mean?

According to the Benzinga Edge’s Stock Ranking methodology, the quality score is a percentile-based measure that evaluates a fund's operational efficiency and financial health on a relative basis, factoring in historical profitability and key fundamental indicators compared to peers.

3 BlackRock Funds Deteriorate In Quality Ranking

The marked deterioration across these three BlackRock funds, namely, BlackRock Credit Allocation Income Trust (NYSE:BTZ), BlackRock Debt Strategies Fund Inc. (NYSE:DSU), and BlackRock Corporate High Yield Fund Inc. (NYSE:HYT), underscores the current challenges plaguing credit sectors, exposing vulnerabilities just as traditional safe havens lose favor amid fluctuating yields.

Blackrock Credit Allocation Income Trust

  • BTZ entered the week with a quality percentile score of 14.9 but ended at just 8.12, representing a week-on-week collapse of 6.78 points.
  • The fund has gained 5.43% year-to-date, and it was down -0.09% over a year.
  • It maintains a stronger price trend over the short, medium, and long terms with a moderate momentum ranking. Additional performance details are available here.

See Also: 4 Tech Stocks That Look Overpriced -- Do You Own One?

BlackRock Debt Strategies Fund Inc.

  • DSU’s fall was even steeper, dropping from a prior percentile ranking of 20.05 to 5.22, a week-on-week change of 14.83 points.
  • Lower by 2.21% YTD, the fund was down 3.63% over the year.
  • With a poor momentum ranking, this fund maintained a stronger price trend over the short and medium terms but a weaker trend in the long term. Additional performance details are available here.

Blackrock Corporate High Yield Fund Inc.

  • HYT also succumbed to market forces, moving from a previously modest score of 16.74 down to 9.11, a weekly decline of 7.63 percentile points.
  • The fund has declined by 3.13% YTD and 5.05% over the year.
  • It had a weak price trend in the short, medium, and long terms and a poor momentum ranking. Additional performance details are available here.

With all three funds now ranking among the market's lowest deciles for quality, investors may seek alternatives that offer stronger balance sheet resilience and higher fundamental quality in an increasingly selective and challenging market landscape.

Price Action

The 10-year Treasury bond yielded 4.03% and the two-year bond was at 3.53%. Whereas the long-term 30-year bond was yielding 4.65% as of the publication of this article.

The SPDR S&P 500 ETF Trust (NYSE:SPY) and Invesco QQQ Trust ETF (NASDAQ:QQQ), which track the S&P 500 index and Nasdaq 100 index, respectively, rose in premarket on Tuesday. The SPY was up 0.18% at $662.10, while the QQQ advanced 0.29% to $593.40, according to Benzinga Pro data.

Read Next:

  • 3 Communication Services Stocks Show Improving Valuations

Disclaimer: This content was partially produced with the help of AI tools and was reviewed and published by Benzinga

Photo: Shutterstock

Continue Reading...

Popular

Trump administration puts on hold $18 billion in funding for New York City infrastructure projects

WASHINGTON (AP) — President Donald Trump's administration said Wednesday it was putting a hold on roughly $18 billion to fund beneath the Hudson River between New York City and New Jersey and the city's expanded project because of .

Benzinga Bulls And Bears: Oracle, Costco, NIO — And Wall Street Snaps Its Slide

Benzinga examined the prospects for many investors' favorite stocks over the last week — here's a look at some of our top stories.

Turn Your "Dead Money" Into $306+ Monthly (Starting This Month) - Ad

I've been tracking a financial revolution that most people don't even know exists yet. It lets you generate $306 to $5,000 per month in retirement income... With 10X less money than what financial advisors say you need! This is a new type of investment you can buy with one click in your brokerage account.

Cathie Wood Dumps $5.2 Million Worth of This AI Stock, Here's What Ark Bought Instead

Ark Invest decided to sell shares of Tempus AI (TEM), despite positive news of FDA clearance for its diagnostic device. They also made other key trades.

Penguin Solutions Q4 Preview: Modest Beat Likely, Analyst Raises Price Target

Penguin Solutions expected to beat estimates in Q4 due to strong memory demand, according to Rosenblatt analyst. Price target raised.

New Biotech Offering Targets $426B Rare Disease Market - Ad

The rare disease drug space is growing fast-and so is investor interest. With exclusivity, pricing power and major M&A moves, the rare disease space is getting interesting. This company has the science and the experience.

Trump files $15 billion defamation lawsuit against The New York Times

NEW YORK (AP) — President Donald Trump filed a $15 billion defamation lawsuit against The New York Times and four of its journalists on Monday, according to court documents.

Trump's Immigration Policies Could 'Shrink' GDP Growth As US Population Projected To Decline, Warns CBO

The U.S. population growth is expected to decline at a faster rate than previously projected due to President Donald Trump's immigration policies, according to the Congressional Budget Office (CBO).

Hit Your Retirement "Freedom Number" (Without $1 Million) - Ad

Retirement should be freedom, not stress. Yet outdated advice and tiny returns leave many trapped. Kelly G. broke free with a revolutionary income strategy once reserved for the wealthy - hitting her "Freedom Number" faster than she dreamed. You might already have enough too.

Democrats plan to force Senate vote on Trump's tariffs on Canada and Brazil

WASHINGTON (AP) — Democrats are planning to force two Senate votes on in the coming weeks, keeping pressure on Senate Republicans as many of them have voiced frustration with the policies.

Nvidia Is About to Shock the World: October 23rd - Ad

Jeff Brown, the tech legend who picked shares of Nvidia in 2016 before they jumped by more than 22,000%, is warning everyone to... Mark this date on your calendar: October 23rd! That's when Nvidia could help send shares of this Elon Musk supplier skyrocketing higher.

Big Tech's energy-hungry data centers could be bumped off grids during power emergencies

HARRISBURG, Pa. (AP) — With the explosive growth of Big Tech's data centers threatening to overload U.S. electricity grids, policymakers are taking a hard look at a tough-love solution: bumping the energy-hungry data centers off grids during power emergencies.

$1000 Invested In Alnylam Pharmaceuticals 5 Years Ago Would Be Worth This Much Today

Alnylam Pharmaceuticals (NASDAQ: ALNY) has outperformed the market over the past 5 years by 10.45% on an annualized basis producing an average annual return of 25.22%. Currently, Alnylam Pharmaceuticals has a market capitalization of $57.78 billion.

Elon's $25 Trillion Confession - Ad

Elon Musk: "Tesla will become a $25 trillion company." That would make Tesla 8x bigger than Apple today. How is that possible? He admits it's all thanks to this one AI breakthrough that will take AI out of our computer screens and manifest a 250x boom here in the real world.

Trump Makes Chinese Stocks Great Again — Until Someone Mentions Tariffs

President Donald Trump's recent optimistic remarks on negotiations with China have given a boost to U.S.-listed Chinese stocks. 

Trump and Xi are set to discuss the TikTok deal and future of US-China relations

WASHINGTON (AP) — U.S. is expected to talk with Chinese leader Xi Jinping on Friday in a push to finalize a deal to allow the popular social media app in the United States.

Hit Your Retirement Income Goal With 10X Less Money - Ad

Financial advisors say you need $1.5M to generate $5,000/month. A revolutionary new investment does it with potentially $150,000. Kelly G: "I updated my spreadsheet and it seems illegal. The income keeps growing." Transform non-dividend stocks like Apple and Tesla into monthly income machines. Bloomberg reports they're "entering a golden era." Simple as buying a stock.

Denmark leads an exercise in Greenland, with Russia in mind at a time of tensions with the US

NUUK, Greenland (AP) — Denmark is leading a military exercise with hundreds of troops from several European NATO members in Greenland, a maneuver that coincides with over the Trump administration's desire for U.S. jurisdiction over the vast Arctic territory.

Benzinga Bulls And Bears: Intel, FedEx, Cracker Barrel — And Markets Close At Record Highs

Benzinga examined the prospects for many investors' favorite stocks over the last week — here's a look at some of our top stories.

Biotech With Multiple Orphan Drugs Is Quietly Opening Its Doors - Ad

A promising biotech developing treatments for rare childhood brain diseases is opening a new raise. Its lead drug has fast-track status, orphan designations, is nearing Phase 2 and backed by a Global Integrator.

US orders Delta and Aeromexico to dissolve their partnership over fairness concerns in Mexico

U.S. Transportation Secretary Sean Duffy is following through on to force Delta and Aeromexico to dissolve their longtime partnership because of his concerns that Mexico isn't being fair to U.S. airlines.

The "Mar-A-Lago Accord" Is Now Underway - Ad

The global order is in chaos. And according to 40-year market veteran Dr. David Eifrig, the biggest controlled demolition of the old monetary order in history could now be here, too. That means if you don't take action today, your wealth could decline by 40%... (Yes, even your cash savings.)

Anthony Scaramucci Says 'All Will Be Well' Amid NAKA Stock Volatility: David Bailey Admits 'Investors Are Down Money'

Anthony Scaramucci, the founder and managing partner of SkyBridge Capital, lent support to David Bailey on Tuesday, whose newly formed Bitcoin (CRYPTO: BTC) treasury company Kindly MD Inc. (NASDAQ:

AquaBounty Technologies Stock Explodes Over 98% After Hours: Here's Why

AquaBounty Technologies saw a massive 98.25% surge in after-hours trading to $2.26, following confirmation that it had met NASDAQ's minimum bid price requirement, resolving its earlier delisting risk.

The Tesla Shock Nobody Sees Coming - Ad

While headlines scream "Tesla is doomed"...Jeff Brown has uncovered a revolutionary AI breakthrough buried inside Tesla's labs. One that is helping AI escape from our computer screens and manifest itself here in the real world all while creating a 25,000% growth market explosion starting as early as October 23rd.

Rivals Compass and Anywhere Real Estate to combine in deal valued at $10 billion including debt

Two of the nation's biggest real estate services companies are combining in a deal that will bring Century 21, Compass and several other major brokerage brands under the same umbrella.

Rare Disease Biotech Offers Access Ahead of Key Milestone - Ad

This late-stage biotech is gearing up for Phase 2 trials with an FDA-designated orphan drug. It's already drawing comparisons to recent billion-dollar exits. Backed by a proven biotech incubator, it's now offering early access to its raise.

uCloudlink's GlocalMe Taps Into U.S. Pet Boom With PetPhone After Market Re-Entry

uCloudlink Group's consumer brand GlocalMe is making a renewed push into the U.S. with the launch of PetPhone, an AI-powered device designed to let pets and owners stay connected.

Turn Your "Dead Money" Into $306+ Monthly (Starting This Month) - Ad

I've been tracking a financial revolution that most people don't even know exists yet. It lets you generate $306 to $5,000 per month in retirement income... With 10X less money than what financial advisors say you need! This is a new type of investment you can buy with one click in your brokerage account.

Toyota and Hyundai recall more than 1.1 million vehicles for seat belt, panel display problems

Toyota and Hyundai are recalling a combined 1.1 million vehicles due to problems with the instrument panel displays and seat belts, U.S. auto regulators said Thursday.

Lam Research And JSR Resolve Legal Disputes As They Team Up On AI Era Chips

Lam Research and JSR Corp agreed to collaborate and cross-license, combining their expertise to accelerate semiconductor manufacturing and reduce costs.

New Biotech Offering Targets $426B Rare Disease Market - Ad

The rare disease drug space is growing fast-and so is investor interest. With exclusivity, pricing power and major M&A moves, the rare disease space is getting interesting. This company has the science and the experience.

AstraZeneca's Fasenra Falls Short In Smoker's Lung Trial

AstraZeneca's Fasenra misses the primary COPD endpoint while Saphnelo's lupus trial shows significant improvements and consistent safety profiles.

Lockheed Martin Counters Boeing's F-47 Victory With Cost-Effective F-35 Upgrade Using Sixth-Gen Technology

Lockheed Martin is countering Boeing's F-47 win with a cost-effective F-35 upgrade that integrates sixth-generation tech, aiming to offer 80% of the F-47's capabilities at half the price.

Hit Your Retirement "Freedom Number" (Without $1 Million) - Ad

Retirement should be freedom, not stress. Yet outdated advice and tiny returns leave many trapped. Kelly G. broke free with a revolutionary income strategy once reserved for the wealthy - hitting her "Freedom Number" faster than she dreamed. You might already have enough too.

Mark Zuckerberg Warns AI Boom Could Mirror Dot-Com Bubble: '...Something Like That Would Happen Here'

Meta CEO Mark Zuckerberg warned that AI could spark a bubble like the dot-com era, saying there is "definitely a possibility" of a market crash, but argued the greater danger lies in underinvesting in what he views as a transformative technology.

Trending Now

Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.

Copyright activatrade.ca
Privacy Policy | Terms of Service