Kiniksa Pharmaceuticals Stock Is Attractive From Valuation Perspective-JP Morgan Analyst

Vandana Singh

March 06, 2025

JP Morgan analyst Anupam Rama issued a note on Thursday maintaining a positive outlook on Kiniksa Pharmaceuticals International (NASDAQ:KNSA), citing Arcalyst’s strong commercial performance and the company's focused pipeline.

JP Morgan maintains the Overweight rating with a price target of $40.

Rama values Kiniksa shares in the low-$30s on Arcalyst alone and estimates a range in the high-$30s to low-$40s when including probability-adjusted KPL-387. The analyst believes the strategic focus on recurrent pericarditis (RP) provides clear opportunities for growth.

“As a result, we think KNSA shares are attractive from a valuation perspective, driven by both the commercial prospects of Arcalyst as well as the undervalued pipeline,” the analyst adds.

In February, Kiniksa Pharmaceuticals released a development update that said it would focus on cardiovascular indications.

The company discontinued abiprubart development in SjÃ¶gren’s Disease. The company will explore strategic alternatives for the asset.
Kiniksa also announced that it has exercised its right to terminate its exclusive license agreement for mavrilimumab with AstraZeneca Plc‘s (NASDAQ:AZN) MedImmune.

Kiniksa is developing KPL-387 for recurrent pericarditis (RP) with a target profile of monthly subcutaneous (SC) dosing.

Recurrent pericarditis is a condition where the pericardium becomes inflamed again after a period of symptom-free time. The pericardium is a sac that surrounds the heart.
Kiniksa is conducting a single ascending dose (SAD) and multiple ascending dose Phase 1 trial of KPL-387 in healthy volunteers.
Kiniksa has interacted with the U.S. Food and Drug Administration (FDA) and expects to initiate a Phase 2/3 trial of KPL-387 in recurrent pericarditis in mid-2025. Phase 2 data are expected in the second half of 2026.

Arcalyst net product revenue was $122.5 million and $417.0 million for the fourth quarter and full year 2024, respectively. The company expects 2025 Arcalyst revenues of $560 million-$580 million.

Price Action: KNSA stock is down 1.6% at $21.04 at last check Thursday.

Read Next:

Taiwan Semiconductor CEO, Taiwan President To Discuss $100 Billion US Expansion, ‘Not Afraid’ Of Losing US Subsidies

Photo: Shutterstock

Recommended

The Most Important "AI Stock" You've Never Heard Of - Ad

Elon Musk Drops Stunning Bombshell? - Ad

Elon's Biggest Secret Could Save Your Retirement - Ad

Popular

CSX profit drops 27% as railroad shipments decline in the first quarter

OMAHA, Neb. (AP) — CSX railroad's profit fell 27% in the first quarter as two major construction projects contributed to a decline in shipments.

Powell says Federal Reserve can wait on any interest rate moves

WASHINGTON (AP) — The Federal Reserve can stay patient and wait to see how tariffs and other economic policies of the Trump administration before making any changes to interest rates, Chair Jerome Powell said Wednesday.

Trump Signals "End of M.A.G.A."

Trump Signals "End of M.A.G.A." - Ad

Trump's new mission: Make America Wealthy Again. And according to ex-CIA advisor Jim Rickards, the U.S. is sitting on a $150 trillion fortune--enough to make every family millionaires. Discover how this hidden wealth could soon change everything.

Here's a look at recent aircraft tragedies, mishaps and close calls

The killed all six on board — a physician couple and their accomplished children and partners — during a family trip to the Catskills.

China May Hit US Where It Hurts Amid Trump's Tariff War â€” Services Trade In Crosshairs, With Walt Disney, IMAX And Warner Bros. Discovery In Focus

As Washington doubles down on its trade war with China, and tariffs now going as high as 104%, some leading experts believe that the Middle Kingdom might have an ace up its sleeve, that could hit the United States where it hurts most—Services.

No.1 Opportunity for 2025 [Take Action Now!]

No.1 Opportunity for 2025 [Take Action Now!] - Ad

Starlink's potential IPO Could Be the Biggest in History--Silicon Valley insider James Altucher has uncovered a way to profit BEFORE the IPO--with as little as $50. Musk's $180B giant is set to launch--will you miss out? Claim your spot before it's too late.

With Nippon Deal In Trump's Court, JPMorgan Turns Cautious On US Steel

JP Morgan downgrades United States Steel (NYSE:X) from Overweight to Neutral and lowers price forecast due to pending NSC deal and potential tariff risks.

Warren Buffett Stands Tall In 2025 As Elon Musk, Jeff Bezos And Mark Zuckerberg Bleed Billions In Net Worth: 'Oracle Of Omaha' Emerges As Lone Gainer Among Top Billionaires Amid Market Rout

Trump's tariff hike causes chaos in global markets, with tech billionaires like Musk, Bezos, and Zuckerberg suffering huge losses.

This Tiny Tech Stock Could Be the Next Big Platform Play

This Tiny Tech Stock Could Be the Next Big Platform Play - Ad

One under-the-radar company is embedding intelligence into everyday glass--already powering Ferraris, aircraft, and city buses with adaptive surfaces and vision systems. It's not just a product. It's a platform.

Musk could be headed for a Washington exit after turbulent times at Trump's DOGE

WASHINGTON (AP) — DOGE’s days appear to be numbered.

Mark Cuban Says Between 'Free Trade' Elon Musk And 'Full Tariff' Trump, It Is The President Who Will Win As Stocks Futures Tank

Elon Musk advocates for zero tariffs while Mark Cuban predicts President Trump's tariff strategy will ultimately succeed, despite causing significant stock declines in major tech companies.

Gold Just Hit Another Record. This Junior Could Be Next.

Gold Just Hit Another Record. This Junior Could Be Next. - Ad

This copper junior was the smallest company invited to a top global mining conference. With nearly 1B pounds CuEq and 50,000m of funded drilling, this story won't stay quiet for long.

Demand for viral 'torpedo' baseball bats has sent a Pennsylvania factory into overdrive

KING OF PRUSSIA, Pa. (AP) — A 70-year-old man who plays in an area senior hardball league popped into Victus Sports this week because he needed bats for the new season. Plus he just had to take some cuts with baseball's latest fad and see for himself if there really was some wizardry in the wallop off

Trump reaches deals with 5 law firms, allowing them to avoid prospect of punishing executive orders

WASHINGTON (AP) — announced deals Friday with five law firms that will allow them to avoid the prospect of a punishing executive order and require them to together provide hundreds of millions of dollars' worth of free legal services for causes his administration supports.

Biggest Dividend Payout in U.S. History: $1 Trillion up for Grabs!

Biggest Dividend Payout in U.S. History: $1 Trillion up for Grabs! - Ad

Trump just launched a $1 trillion National Investment Fund to replace income taxes and send direct payouts to Americans. You could claim up to $21,307--before the first public checks go out. This is historic. Act now to be first in line.

Cathie Wood Doubles Down: Mops Up Another $1.39 Million Worth Of Robinhood Stock Amid Trump Tariff Dip

On Thursday, April 3, 2025, Cathie Wood-led Ark Invest purchased Robinhood stock worth $1.39 million amid a broader market slump.

Dow wants to power its Texas manufacturing complex with new nuclear reactors instead of natural gas

Dow, a major producer of chemicals and plastics, wants to use next-generation nuclear reactors for clean power and steam at a Texas manufacturing complex instead of natural gas.

The Next Big Breakout Isn't a Chip. It's Glass.

The Next Big Breakout Isn't a Chip. It's Glass. - Ad

Smartphones disrupted phones. EVs disrupted autos. Now smart surfaces are disrupting everything--and one overlooked company is at the center of it.

Immigration officials raid Washington state roofing company and arrest over 3 dozen people

BELLINGHAM, Wash. (AP) — Federal immigration agents arrested 37 people Wednesday during a raid at a roofing business in northern Washington.

Jeff Bezos Italian Wedding Guest List And Plans: Kim Kardashian, Donald Trump, Bill Gates, Oprah Winfrey Get Reported Invites

Jeff Bezos and Lauren Sanchez are set to wed this year. Reports of a June wedding in Italy show the $500 million superyacht Koru could be used.

Pre-IPO Access Starts Here

Pre-IPO Access Starts Here - Ad

By the time today's biggest companies--SpaceX, OpenAI, Anthropic--go public, early opportunities may already be gone. Augment Markets change that. We provide accredited investors with access to private securities, liquidity for employees, and real-time pricing--so you can invest before the IPO.

Bogus report on tariff pause briefly lifted markets before White House denied it

NEW YORK (AP) — A bogus rumor that President Donald Trump was considering a pause in tariffs briefly lifted markets Monday before the White House shot down the unfounded reports.

Dan Ives Cuts Tesla Target To $315, Slashes Apple By 23% Amid Tariff Fallout, Warns Elon Musk-Led EV Maker Faces 'Darker Days' Ahead

Wedbush Securities analyst Dan Ives has lowered his Tesla Inc. price target to $315 from $550 while maintaining an "outperform" rating, citing growing concerns about the electric vehicle maker's brand perception and softening demand.

New Study: 50 Stocks Will Crash While 7 MAGA Stocks Will Soar

New Study: 50 Stocks Will Crash While 7 MAGA Stocks Will Soar - Ad

If you own any of these stocks -- directly or through mutual funds -- I want to encourage you to sell them before April 30th. I've compiled all 50 companies in my "MAGA Blacklist" report. Your retirement could depend on seeing this list.

Bitcoin Plunges Below $80,000, Ethereum, Dogecoin Crash As Cryptocurrencies Mirror Stocks Amid Trump Tariff Mayhem: Analyst Flags 'Critical Support Level' For BTC (UPDATED)

Editor’s Note: This story has been updated to provide more clarity on how stocks reacted to the Tariff announcement Leading cryptocurrencies suffered a bloodbath on Sunday as concerns over President Donald Trump's tariff policies deepened.

Voices from coal country say closures of MSHA offices will endanger mine safety

CHARLESTON, W.Va. (AP) — Retired coal miner Stanley “Goose” Stewart questions whether it's safe for anyone to work in the industry right now.

Copper's Spiking--And This Junior Has the Grades to Match

Copper's Spiking--And This Junior Has the Grades to Match - Ad

Copper is climbing again--and this time, it looks tariff-proof. A $31M junior just posted nearly 1B lbs of copper equivalent. With insiders and institutions piling in, this could be the next breakout.

Defense Secretary Hegseth Under Fire for Bringing Wife To High-Level Security Meetings

Defense Secretary Pete Hegseth has reportedly been taking his wife to high-level foreign meetings where sensitive information was discussed.

Apple Revamps Leadership, Preps New Vision Pro Headsets Amid Commercial Hurdles

Apple is reportedly gearing up to introduce two new Vision Pro headsets and revamp its iPadOS.

Putting Your Name on This List Could Hand You $1,270 on Friday

Putting Your Name on This List Could Hand You $1,270 on Friday - Ad

URGENT: On Tuesday, a simple set of instructions will be sent out to an elite group of investors. The folks in this group will have the opportunity to place a 10-minute trade that could double their money by Friday. Consider this your invitation to join them. The next trade is just days away.

China Markets Up, Europe Tumbles As Trade War Escalates; Oil Hits Multi-Year Low - Global Markets Today While US Slept

US markets closed lower on 04/08 amid trade war fears and weak economic data. Asian markets followed suit with sharp declines, while European shares also fell as recession concerns grew. Oil prices dropped to multi-year lows, and the US dollar slumped as investors anticipate deeper rate cuts by the Federal Reserve.

One Tech Tip: Don't give your email to strangers, use a decoy address instead

LONDON (AP) — You've heard of burner phones. What about burner email?

From Ferrari to Bombardier--This Tiny Company Is Everywhere

From Ferrari to Bombardier--This Tiny Company Is Everywhere - Ad

A $150M disruptor is transforming glass into real-time displays and vision systems. Already embedded in global OEMs and Tier 1s, it's scaling fast--yet still under Wall Street's radar.

XRP, Solana, Cardano Plunge Over 15% In 7 Days: Is A Rebound Coming?

Major altcoins like XRP (CRYPTO: XRP), Solana (CRYPTO: SOL) and Cardano (CRYPTO: ADA) are down more than 15% in the past seven days, tracking

Trump Family Deepens Crypto Ties With Nearly $1 Billion on the Line

The Trump family has made substantial investments in the cryptocurrency industry.

World Economic Forum: "Arguably the Most Exciting Human Discovery Since Fire"

World Economic Forum: "Arguably the Most Exciting Human Discovery Since Fire" - Ad

Sam Altman, Bill Gates, and Mark Zuckerberg are all investing vast sums of money into a radical technology. According to Bloomberg, this could become 10 times bigger than AI, quantum computing, electric vehicles, cryptocurrencies, and robotics combined. And one stock is at the center of it all.

Expect more fake eggs made of colored marshmallows or even potatoes on this year's Easter spread

MISSION, Kan. (AP) — With egg prices high, the internet has offered up a host of alternatives, with crafters painting rocks and influencers dyeing everything from marshmallows to potatoes.

Apple's iPhone Stockpile Could Disrupt Supply Chain Amid Looming Chip Tariffs, Warns Top Analyst â€” Identifies Cupertino's Best Option Beyond White House Talks

Apple has temporarily avoided steep U.S. tariffs on China-made products, but analyst Ming-Chi Kuo warns the company's preemptive iPhone stockpile and ongoing trade risks could disrupt its supply chain—making India-based production its best long-term safeguard.

Brace Yourself for Jeff Bezos' "Amazon Helios"

Brace Yourself for Jeff Bezos' "Amazon Helios" - Ad

Amazon delivers 20 million packages a day... powers some of the most popular websites... delivers medication to half of the U.S. population... and even produces award-winning films and TV shows. But a Wall Street legend -- twice featured on 60 Minutes -- predicts that "Amazon Helios" will be bigger than all of those... COMBINED.

Trump Administration Opens Probe Into Foreign Drug Imports, Eyes Tariffs Under National Security Law

The U.S. Commerce Department has launched a Section 232 investigation into the national security impact of pharmaceutical and drug ingredient imports, citing supply chain risks.

Trending Now

Peter Schiff Says Nike 'Won't Build Factories' In US, They Will Sell To Countries Like China: A Much Better Strategy Amid Trump Tariffs

Anthony Scaramucci Says 26 Years Ago Warren Buffett's Amazon Caution Cost Him Millions: Former Trump Official Sees Today's AI Hype As History Repeating