World Economic Forum: "Arguably the Most Exciting Human Discovery Since Fire"

Sam Altman, Bill Gates, and Mark Zuckerberg are all investing vast sums of money into a radical technology. According to Bloomberg, this could become 10 times bigger than AI, quantum computing, electric vehicles, cryptocurrencies, and robotics combined. And one stock is at the center of it all.

Bristol Myers Acquired MyoKardia Drops Fulcrum Agreement, Ending Cardiomyopathy Research Deal

Vandana Singh
March 05, 2025

Fulcrum Therapeutics, Inc. (NASDAQ:FULC) received written notice from MyoKardia, Inc. for the termination of the collaboration and license agreement dated July 20, 2020.

Under the agreement, Fulcrum had granted MyoKardia an exclusive worldwide license to discover, develop, and commercialize novel targeted therapies for genetic cardiomyopathies.

Also Read: Fulcrum Therapeutics Suspends Rare Muscular Disease Candidate After Disappointing Data From Pivotal Trial

Under the agreement, under a mutually agreed research plan, Fulcrum agreed to perform assay screening and related research activities to identify and validate up to a specified number of potential cardiomyopathy gene targets for further research, development, manufacture, and commercialization by MyoKardia.

MyoKardia paid Fulcrum $10.0 million upfront and $2.5 million in prepaid research funding. It also agreed to reimburse Fulcrum for the costs of research activities not covered by the prepaid research funding up to a maximum of the total research funding.

Upon the achievement of specified milestones, Fulcrum would have been entitled to preclinical milestone payments, development milestone payments and sales-based milestone payments of up to $298.5 million in the aggregate per target for certain identified targets, and of up to $150.0 million in the aggregate per target for certain other identified targets.

Fulcrum achieved a $2.5 million specified preclinical milestone. MyoKardia also agreed to pay Fulcrum tiered royalties ranging from a mid-single-digit percentage to a low double-digit percentage.

In 2020, Bristol Myers Squibb Co (NYSE:BMY) acquired MyoKardia for $13.1 billion.

As per the SEC filing, the termination will become effective on June 26, 2025.

Price Action: FULC stock is up 1.38% at $3.32 at the last check Wednesday.

Read Next:

Continue Reading...

Popular

Warren Buffett's Top Stock Picks Now Come With a 15% Income Bonus Through This Fund

A new ETF is offering investors the chance to follow in the footsteps of one of the world's most successful investors and earn income at the same time.

Why Barrick Gold Stock Is Trading Lower

Barrick Gold Corp (NYSE:GOLD) shares are trading lower by 4.5% to $19.08 during Wednesday’s session.

Nvidia Is About to Shock the World: July 23rd - Ad

Jeff Brown, the tech legend who picked shares of Nvidia in 2016 before they jumped by more than 22,000%, is warning everyone to... Mark this date on your calendar: July 23rd! That's when Nvidia could help send shares of this Elon Musk supplier skyrocketing higher.

Canadians put off by Trump's bluster and border arrests are booking far fewer US visits

VANCOUVER, British Columbia (AP) — Diana and Rick Bellamy initially planned to take a Caribbean cruise out of Houston before heading to Laurel, Mississippi, to visit the home of one of their favorite HGTV shows, “Home Town.”

Gold's Historic Surge Unlocking Value in These Mining Stocks

Surging gold prices have amplified the profitability of global gold mining companies. Here are some stocks to consider.

The Most Important "AI Stock" You've Never Heard Of - Ad

The AI revolution is moving faster than anyone expected. But what no one is talking about is the one company AI simply can't exist without. It may be the single most important AI investment, yet most people don't even know its name. For now. The moment Wall Street catches on, this $20 stock could explode.

Mike Pence Says Trump Comeback 'Unrivaled' In Modern American History But Only Return To Values Of First Term Will Ensure President's Legacy

Mike Pence praised Trump's early second-term achievements but warned that abandoning conservative principles—especially on Ukraine and tariffs—could threaten both America's future and Trump's legacy.

UPS to cut 20,000 jobs, close some facilities as it reduces amount of Amazon shipments it handles

UPS is looking to slash about 20,000 jobs and close more than 70 facilities as it drastically reduces the amount of Amazon shipments it handles.

"Market Wizard " Thrives on Tariff Turmoil - Ad

Steel. Copper. Semiconductors. Another round of tariffs is rattling Wall Street, triggering panic selling. But history shows these policy moves don't just create losers - they create massive trading opportunities.

Alexandria Ocasio-Cortez Asks,'How Much Did Majorie Taylor Greene Make When She Bought The Dip?'

"Just how much did Marjorie Taylor Greene make when she bought the dip?" Alexandria Ocasio-Cortez asks in the caption of a YouTube video calling for a ban on Congressional trading.

Trump's Autonomous Vehicles Stance, Bezos Vs. Tesla, And More: This Week In Mobility

Autonomous driving & EV have seen significant developments this week: Trump's change of heart, Bezos-backed startups, & Tesla's declining sales.

You Can Take a Stake in Elon's xAI Before June 1st... - Ad

Elon Musk's private AI firm xAI may have just leapfrogged ChatGPT and Google's Gemini--building what experts call the future of AI. For the first time, you can take a stake starting at $500.

Take Investment Advice From Shaq — His Fortune Grew Thanks To Charles Barkley and Donuts

Former NBA player Shaquille O'Neal has seen a significant increase in his wealth, quadrupling his net worth through an investment strategy inspired by Amazon's CEO, Jeff Bezos.

Jeff Bezos Wants To Send You To Space After Katy Perry: Here's How Much A Reservation With Blue Origin Costs

Blue Origin is taking reservations for its next trips to space after sending pop star Katy Perry there. Here's how much a reservation costs.

This Intercept Stopped the Gold Sector Cold - Ad

114.26 g/t over 10.6m. That's not a typo. And it wasn't deep exploration-it was in an active mining zone.

Odyssey Marine Exploration Stock Surges On Continued Momentum: What's Going On?

Odyssey Marine Exploration Inc. (NASDAQ: OMEX) shares are trading higher Thursday, extending the momentum from a major intraday spike driven by reports of a forthcoming U.S. executive order favoring the deep-sea mining industry.

Eli Lilly Set To Report Earnings As Investors Eye Weight Loss Drug Momentum

Eli Lilly (LLY) will report Q1 results on Thursday. Analysts expect in line results with focus on tirizepatide and obesity franchise.

No.1 Opportunity for 2025 [Take Action Now!] - Ad

Starlink's potential IPO Could Be the Biggest in History--Silicon Valley insider James Altucher has uncovered a way to profit BEFORE the IPO--with as little as $50. Musk's $180B giant is set to launch--will you miss out? Claim your spot before it's too late.

Activists to rally worldwide on May Day, with US protests targeting Trump policies

CHICAGO (AP) — From worker rights rallies to marches for social justice, activists around the globe will kick off demonstrations on Thursday.

Buffett Dismisses Rumors Of Stockpiling Cash For Successor Greg Abel: 'I Wouldn't Do Anything Nearly So Noble Just So Greg Could Look Good'

Berkshire Hathaway chief Warren Buffett, has put to rest rumors that he is accumulating a substantial cash reserve for his successor, Greg Abel.Berkshire Hathaway Inc. (NYSE:BRK.A) chief Warren Buffett, has put to rest rumors that he is accumulating a substantial cash reserve for his success

Trump's Crypto Blueprint Unveils This Infrastructure Powerhouse - Ad

One blockchain token sits at the heart of Washington's pro-crypto agenda. Institutions are loading up while it still trades at a discount. Here's how to get in for $3.

Forget Dogecoin And Shiba Inu — Crypto Analyst Sees This Coin Surging 100%

A crypto analyst has forecasted a 100% increase for Pepe (CRYPTO: PEPE), a mid-cap competitor to Dogecoin (CRYPTO: DOGE) and Shiba Inu (CRYPTO:

Tens of thousands of Los Angeles County workers begin 2-day strike

LOS ANGELES (AP) — More than 50,000 Los Angeles county workers began a two-day strike Monday evening, closing libraries and disrupting administrative operations across the nation's most populous county.

The Cross-Chain Giant Set for 1,000%+ Gains - Ad

This multi-chain protocol's volume is exploding while its price is still under the radar. Institutions are moving in fast-get our urgent report before retail wakes up.

Brag, Burn, Learn: ZJK Industrial's Costly Nvidia Lesson

After briefly flirting with global fame and the volatility that accompanied it, this firm seems to have learned its lesson.

Eliott to celebrate NAPA's 100th anniversary with gold car. Credits company for his NASCAR career

CHARLOTTE, N.C. (AP) — Chase Elliott, son of a NASCAR Hall of Famer and the sport's most popular driver, has 19 career Cup Series wins and championship titles in both the Cup and Xfinity Series.

Biggest Dividend Payout in U.S. History: $1 Trillion up for Grabs! - Ad

Trump just launched a $1 trillion National Investment Fund to replace income taxes and send direct payouts to Americans. You could claim up to $21,307--before the first public checks go out. This is historic. Act now to be first in line.

Applied Digital (APLD) Secures $150M Preferred Equity Deal: What's Going On?

Applied Digital shares are trading higher by 14% during Thursday's session. The company announced it had entered into a Preferred Equity Purchase Agreement with select investors.

Swiss leader says Trump administration foresees 'privileged' talks with 15 countries on US tariffs

GENEVA (AP) — The Swiss president says Switzerland is among 15 countries with which the United States plans to conduct “privileged” negotiations to help reach a deal in the wake of sweeping U.S. tariffs on dozens of countries that have shaken global markets.

A New Gold Discovery in Red Lake? - Ad

Two new gold anomalies just lit up the maps. They sit right beside a restart-ready mine-and follow the exact fold pattern that's made Red Lake world famous.

World Liberty's Stablecoin In $2 Billion Deal, SoFi Reintroduces Crypto And Riot Platforms' Q1 Results: This Week In Crypto

The weekend was a whirlwind of activity in the financial world, with a particular focus on cryptocurrencies. From Peter Schiff’s surprising preference for Dogecoin over Bitcoin to Riot Platforms’ Q1 results, there was no shortage of intriguing developments. Let’s dive into the top stories. Peter Schiff Prefers Dogecoin Over Bitcoin

Rocket Lab Stock Is Shooting Higher Thursday: What's Fueling The Launch?

Rocket Lab USA Inc (NASDAQ:RKLB) shares are trading higher Thursday after the company announced it was selected by Kratos Defense & Security Solutions Inc (NASDAQ:KTOS) to provide a hypersonic test flight for the U.S. Department of Defense (DOD).

Executive Order 14179 Could Change Social Security Forever - Ad

President Trump's inner circle has a plan that could radically change how Social Security works. In fact, just days after taking office, President Trump signed Executive Order 14179 - giving his team new powers to permanently reset how many key federal agencies work. That reset is now ready to begin... and it's critical you start preparing your money immediately.

Elon's Greatest Invention... Hidden in South Memphis? - Ad

Tech legend Jeff Brown recently traveled to the industrial zone of South Memphis to investigate what he believes will be Elon's greatest invention ever... Yes, even bigger than Tesla or SpaceX.

Shiba Inu's Shibarium Is Booming — Here's What's Driving the 54% Transaction Surge

Shibarium, the Layer-2 blockchain of Shiba Inu (CRYPTO: SHIB), has reported a significant 54% increase in transactions. This surge indicates a growing interest and engagement in the network.

World Economic Forum: "Arguably the Most Exciting Human Discovery Since Fire" - Ad

Sam Altman, Bill Gates, and Mark Zuckerberg are all investing vast sums of money into a radical technology. According to Bloomberg, this could become 10 times bigger than AI, quantum computing, electric vehicles, cryptocurrencies, and robotics combined. And one stock is at the center of it all.

The more Trump talks about making trade deals, the more confusing the tariff picture gets

WASHINGTON (AP) — The more talks about his efforts to reach deals with America's trading partners, the more confusing picture gets. His team seems good with that, saying Trump is using “strategic uncertainty” to his advantage.

Trending Now

Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.

Copyright activatrade.ca
Privacy Policy | Terms of Service